(Editor's note, 5/27: The story and headline have been updated to reflect a Cole County judge's changes to the amount of money awarded in the case.)

The Western District Court of Appeals upheld a Cole County jury's decision to punish agriculture giant Monsanto for diseases developed by those using its product.

The three-judge panel unanimously agreed with the 2023 decision. The court denied all seven points of Monsanto's appeal, ranging from testimony and evidence allowed to the amount of money Monsanto was ordered to pay.

Three people, including one from Eldon, Missouri, sued Monsanto in 2022 after they developed non-Hodgkin lymphoma. All of them blamed the use of Monsanto's Roundup weed killer and the product's use of glyphosate for their cancer. A jury heard the case for a month in the fall of 2023, sided with the three plaintiffs and ordered Monsanto to pay them $1.56 billion. Judge Daniel Green lowered that award to $611.1 million following post-trial motions from Monsanto.

The 73-page decision from the appeals court sided with Judge Daniel Green in admitting reports and testimony about glyphosate and Roundup's cancer-causing potential.

Health and environmental groups have challenged the Environmental Protection Agency's decision to classify glyphosate as "not likely" to cause cancer, questioning the data and conflicts gathered in various reports.

A company spokesperson told ABC 17 News that it would seek a further review of the case and the decision. Monsanto has also asked the U.S. Supreme Court to review similar claims over product warning labels.

"We continue to believe that the trial court committed significant errors by allowing inadmissible and prejudicial testimony into the courtroom which poisoned the jury against the company," the spokesperson said. "These errors resulted in an unconstitutionally excessive punitive damage award. Even after the verdict was reduced, the ratio of punitive to compensatory damages is 9:1, which we believe is excessive and unconstitutional."