For as limited as Oklahoma has looked at times, the Sooners are 3-point road favorites against a Mizzou that could be down its starting quarterback. Read more in our college football picks below. The math for the Oklahoma Sooners is simple. Win one of the next three matchups against SEC-ranked teams, and they guarantee a bowl game. Their first shot comes against the Missouri Tigers on Saturday, and our Oklahoma vs. Missouri predictions expect the Sooenrs to deliver.
Oklahoma -3 ( -110 at BetMGM )
Picks made at time of writing may not reflect live odds. My analysis
The Missouri Tigers had their two-game win streak shattered with a 34-0 drubbing at the hands of then-15th-ranked Alabama. Not only did they get smacked around, but quarterback Brady Cook left for the second straight game with an injury and remains a question mark for this game. If he can’t play, former Notre Dame pivot Dew Pyne will get the start. He didn’t exactly rally the troops against the Crimson Tide, going 6-for-12 for 42 yards and three interceptions. It’s likely the Oklahoma Sooners will try to force Pyne to beat them with the pass, as OU’s run defense is 17th-best in the nation, holding teams to 106.1 yards per game. Meanwhile, Jackson Arnold is on an upward trajectory after getting renamed the starter. He was solid in a 59-14 obliteration of Maine, going 15-for-21 for 224 yards and two TDs, helping OU bust out of a three-game losing skid. Arnold now has four TD tosses and no interceptions in the last two games while completing passes at better than a 70% rate. If OU can welcome back pass catchers Jalil Farooq and Deion Burks from injury, that could really help its quarterback find a rhythm. Mizzou is not to be taken lightly on defense, though, as it holds opponents to under 300 yards of offense per game and boasts a Top-10 passing defense in college football, allowing just 164.8 yards per game.
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Oklahoma vs Missouri prediction and best bet
My best betOklahoma -3 ( -110 at BetMGM )
Picks made at time of writing may not reflect live odds. My analysis
The Missouri Tigers had their two-game win streak shattered with a 34-0 drubbing at the hands of then-15th-ranked Alabama. Not only did they get smacked around, but quarterback Brady Cook left for the second straight game with an injury and remains a question mark for this game. If he can’t play, former Notre Dame pivot Dew Pyne will get the start. He didn’t exactly rally the troops against the Crimson Tide, going 6-for-12 for 42 yards and three interceptions. It’s likely the Oklahoma Sooners will try to force Pyne to beat them with the pass, as OU’s run defense is 17th-best in the nation, holding teams to 106.1 yards per game. Meanwhile, Jackson Arnold is on an upward trajectory after getting renamed the starter. He was solid in a 59-14 obliteration of Maine, going 15-for-21 for 224 yards and two TDs, helping OU bust out of a three-game losing skid. Arnold now has four TD tosses and no interceptions in the last two games while completing passes at better than a 70% rate. If OU can welcome back pass catchers Jalil Farooq and Deion Burks from injury, that could really help its quarterback find a rhythm. Mizzou is not to be taken lightly on defense, though, as it holds opponents to under 300 yards of offense per game and boasts a Top-10 passing defense in college football, allowing just 164.8 yards per game.
Oklahoma vs Missouri same-game parlay (SGP)
Someone being undervalued is Mizzou receiver Theo Wease Jr., who had just two catches for 19 yards against Alabama, and now his line is set at 39.5 receiving yards — a number he'd passed in his previous six starts. Pyne has something to do with this line, but if the backup pivot does get the start, he can’t be worse than he was last week — and neither will Wease Jr. Learn how to bet a same-game parlay with these helpful tips and strategies.Best Oklahoma vs Missouri bonus
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Oklahoma vs Missouri betting trend to know
Oklahoma has cashed the first-ha;lf moneyline in six of its last 11 games for +6.25 units and a 14% ROI. Find more college football betting trends for Oklahoma vs Missouri.Oklahoma vs Missouri game info
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