Ryan O'Hearn and the Baltimore Orioles will square off against Steven Kwan and the Cleveland Guardians at Oriole Park at Camden Yards in the first of a three-game series, Tuesday at 7:05 p.m. ET. The Guardians are listed as +127 moneyline underdogs for this matchup against the Orioles (-151). Baltimore is a 1.5-run favorite (at +142 odds). The contest's total has been set at 8.5 runs.

Here is everything you need from a betting perspective on the Orioles-Guardians game, regarding the run line, moneyline and total, plus expert picks.

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Royals vs. Guardians Highlights | MLB on FOX



Orioles vs. Guardians Game Information & Odds



Orioles vs. Guardians Prediction



Orioles vs. Guardians Betting Insights



Orioles Recent Betting Performance



Orioles Recent Stats



Orioles Player Insights



Orioles Team Props



Guardians Recent Betting Performance



Guardians Recent Stats



Guardians Player Insights



Guardians Team Props



Royals vs. Guardians Highlights | MLB on FOX



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