NFL Championship Weekend 2025 is upon us and both conference title games will take place on Sunday. The 2025 NFC Championship Game will feature the Philadelphia Eagles taking on the Washington Commanders in a 3 p.m. ET kickoff. The 2025 AFC Championship Game will be between the Kansas City Chiefs and Buffalo Bills at 6:30 p.m. ET. The latest Championship Weekend NFL odds list the Eagles as six-point favorites over their divisional rivals, while the Chiefs are 1.5-point favorite at home over the Bills. Both are unchanged from the opener. Before you make any NFL Championship Weekend picks for the 2025 NFL Playoffs, you need to see the NFL against the spread, NFL over-under, and NFL money line predictions powered by the self-learning SportsLine AI.

Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine's Data Science team, AI Predictions and AI Ratings are generated for each game. The AI predictions are determined by statistically learning from each team's historical data and then quantitatively evaluating the strength of the opponent's defense by assigning a numeric value out of 100 called a matchup score.

Once a prediction is formulated, the AI rating is generated using the prediction, the matchup score, and the odds of the market. For example, you could see an A-rating on an over bet if a team is facing a poor defense, their prediction differs from the line and there are favorable odds.

In addition, SportsLine AI is the first fully automated predictive model at SportsLine. It continuously refreshes on the most recent available data and can help you spot the biggest discrepancies in the lines. SportsLine's AI PickBot has hit a whopping 1,390 4.5- and 5-star NFL prop picks since the start of last season at 48% accuracy. Unders of any grade hit at a 54.5% clip. It has also gone 8-2-1 on its A+-rated picks during the 2025 NFL Playoffs.

For divisional round NFL betting, the AI PickBot has evaluated the NFL odds and provided NFL betting picks for all four games. You can only see the AI predictions for the 2025 NFC Championship Game and 2025 AFC Championship Game here.

Top NFL Championship Week AI picks

After analyzing the 2025 NFC Championship Game and 2025 AFC Championship Game, the AI PickBot says the Chiefs cover as 1.5-point home favorites against the Bills on Sunday (O/U 47.5). Buffalo managed a 30-21 victory over the Chiefs during the regular season, but that matchup took place in Buffalo and now the Bills will have to head to Arrowhead Stadium, where their championship hopes have been dashed in recent seasons.

Buffalo has been eliminated from the NFL playoffs three of the last four seasons by Kansas City (2021, 2022 and 2024) and two of those games were played at Arrowhead. This is the seventh year in a row that Kansas City has been to the AFC Championship Game and Patrick Mahomes has led the team to three Super Bowls in the last five years.

Meanwhile, Josh Allen might be the NFL MVP frontrunner, but the Bills haven't reached this stage of the NFL postseason in four years and he'll have to overcome a Chiefs squad that is a perfect 9-0 at home this year. The AI PickBot rates a Kansas City cover as a B-rated pick and also predicts a final score of 26-23. See its other 2025 AFC Championship Game and 2025 NFC Championship Game score predictions and football picks at SportsLine.

How to make AFC Championship Game and NFC Championship Game predictions

The AI PickBot has generated three other NFL picks it has given a B grade or higher. You need to see the AI PickBot's NFL picks before making any NFL Championship Weekend bets of your own. You can only see them at SportsLine.

Who wins and covers each NFL conference championship game, and which top picks should you target now? Visit SportsLine now to see the top NFL picks against the spread, over-under, and on money line, all from the self-learning SportsLine AI PickBot that has nailed 1,390 top-rated picks since the start of last season and is 8-2-1 on A+ rated NFL postseason picks.