From classic comfort food to experimental entrees, Baltimore is serving up the goods with these American spots.

Baltimore is a foodie destination, especially for American cuisine. We've rounded up some of the best restaurants in the city that serve up brunch, burgers, and everything in between (brunch burgers, anyone?)

Here are our picks for the best American restaurants in Baltimore:


cajun shrimp from maisy's, courtesy of restaurant website

Courtesy of Maisy's

Noted for their crab cakes, Maisy's offers a variety of brunch, lunch, and dinner options that will satisfy any palette. Enjoy Jamie's Red Velvet Chicken and Waffles with scrambled eggs and homefries, or try the breakfast burrito. For dinner? Mom's Homemade Meatloaf or Maisy's Coca-Cola Short Ribs should do the trick. They also have happy hour from Monday to Friday, with killer deals on beverages and appetizers. Only a stone's throw away from Inner Harbor, it's the perfect spot to bring out-of-towners looking for local flavor. View their menu here.

Address: 313 North Charles Street

City Cafe

burger and fries from city cafe, courtesy of facebook

Courtesy of Facebook

City Cafe may provide a sophisticated ambiance to their dining space, but the food is all-American comfort. Their menu has favorites like burgers and salads along with creative entrees like the Mixed Grill Jambalaya. For first-timers, we recommend the Baltimore Club Sandwich – a Mid-Atlantic take on the BLT featuring a crab cake, shrimp salad, lettuce, tomato, and bacon on a potato bun. They also have daily specials ranging from Steakhouse Mondays to Pasta Night. View their menu here.

Address: 1001 Cathedral Street

Wicked Sisters

entrees from wicked sisters

Courtesy of Facebook

Located in the trendy Hampden neighborhood, Wicked Sisters is hip to the bone. Their approach to American cuisine is always modern, crafting delicious entrees with only the freshest ingredients. Go classic with the Carbonara or try something different with the Everything Bagel-Crusted Salmon (yes, please). Their cocktail menu is full of playful concoctions, with names like "Mule It Over" and "BBB Betty And The Fernets." You'll want to make this your neighborhood hangout! View their menu here.

Address: 3845 Falls Road

What do you think of this list? Are there any that we missed? Drop us a line in the comments – we'd love to hear from you!