Brock Purdy's pass was tipped at the line and the
Arizona Cardinals snatched the ball from the air to secure a much-needed victory in San Francisco. Seconds earlier,
Chad Ryland kicked a 35-yard field goal that put the Cardinals up 24-23. Arizona trailed 23-10 at the half but scored 14 unanswered points in the second. Kyler Murray was 19-for-30 passing for 195 yards and a touchdown and one interception. Murray had seven carries for 82 yards, including a 50-yard touchdown run on the Cardinals' second play of the game. James Conner, who was quiet in the first half, piled up 86 yards on 19 carries. Michael Wilson had five catches for 78 yards, while Trey McBride returned from injury with six catches for 53 yards. Ryland, kicking for injured Matt Prater, was 3-for-4 on field goals. Kyzir White had the game-securing interception. Mack Wilson had an interception and fumble recovery. Budda Baker has 12 tackles. San Francisco QB Brock Purdy was 19-for-25 for 244 yards and a touchdown. He was intercepted twice and sacked twice. Jordan Mason led the
49ers with 89 yards on 14 carries. Brandon Aiyuk had 147 yards on eight catches — most of which came in the first half. Look back at our updates of the game, which was played at Levi's Stadium in Santa Clara, California.
Cardinals grab late lead
Chad Ryland kicked a 35-yard field goal with 1:40 remaining to give the Arizona Cardinals the lead. Ryland was elevated from the practice squad for the game. He was 3-for-4 on field goals, with one being blocked and returned by the 49ers for a touchdown. Arizona trailed 23-10 at the half but scored 14 points, while shutting out the 49ers in the second half.
Cardinals force turnover
Jesse Luketa punched the ball away and Mack Wilson recovered the fumble for the Cardinals. The 49ers were at the Arizona 8 and looking to put the game out of reach. Jordan Mason got the carry for San Francisco and was fighting to get back to the line of scrimmage when the ball was knocked free. Luketa was inactive for the previous four games.
Cardinals keeping it interesting
Elijah Higgins tapped his toes at the back of the endzone for the Cardinals second touchdown of the game. It was a pass of 2 yards from Kyler Murray. A penalty against the 49ers on the play gave the Cardinals the ball on the 1 for the extra point attempt. Murray handed off to James Conner, who powered in for two points. Conner and Michael Wilson featured heavily on the drive. Wilson caught three passes for 24 yards.
Cardinals get James Conner involved
It took a while, but the Cardinals finally got running back James Conner involved. At the end of three quarters, Conner has 10 carries for 35 yards. In the first half, he had just 9 yards. He also has two catches for 14 yards. While his numbers are below his average, it has given a dimension to the offense that was missing.
Cardinals cut 49ers lead to 10
Mack Wilson intercepted Brock Purdy's pass intended for George Kittle. The Cardinals turned the possession into a 42-yard field goal by Chad Ryland. The pass was tipped at the line by Roy Lopez. Arizona got the ball on the 49ers 25 but wasn't able to move the ball.
Cardinals first-half numbers
Quarterback Kyler Murray is 8-for-15 for 131 yards with an interception. Murray is also the team's leading rusher with three carries for 66 yards and a touchdown. James Conner is the only other ball carrier for the Cardinals. He has six carries for 9 yards. Murray has targeted five different receivers. Michael Wilson has two catches for 54 yards. Arizona is 2-for-5 on third down and 0-for-1 in the red zone. The Cardinals have not been penalized.
49ers first-half numbers
Quarterback Brock Purdy is 12-for-23 for 165 yards and a touchdown. Brandon Aiyuk has six catches for 115 yards. Four different 49ers have caught passes. Jordan Mason leads the 49ers with seven carries for 49 yards. San Francisco has a total of 88 rushing yards. The 49ers have two penalties for 15 yards. They have not turned the ball over. They are 1-for-4 in the red zone and 4-for-8 on third down.
Mitch Wishnowsky makes first career field goal
San Francisco punter Mitch Wishnowsky kicked his first career field goal. 49ers kicker Jake Moody was injured earlier in the game, leaving Wishnowsky as the team's best option when the clock ticked down in the first half. Wishnowsky's attempt was from 26 yards. Holding was fullback Kyle Juszcyk because Wishnowsky is the usual holder on field goals.
Nick Bosa interception gives 49ers a boost
At 6-foot-4 and over 250 pounds, Nick Bosa is a hard man to miss. But Kyler Murray did just that on a second-and-6 pass at the 49ers 24. Murray's screen pass was intended for James Conner. It hit Bosa squarely in the hands. Murray is 8-for-15 for 131 yards. He has three carries for 66 yards and a touchdown.
Blocked FG costs Cardinals 10 points
The Cardinals lined up for a 45-yard field goal. Instead of getting 3 points, the kick by Chad Ryland was blocked by Jordan Elliott. Deommodore Lenoir recovered the ball and returned it 61 yards for a 49ers touchdown. The play, which should have allowed the Cardinals to tie the game, instead saw them fall behind by 10. Ryland is kicking for the Cardinals with Matt Prater injured. Arizona hasn't had a field goal blocked in more than 40 years.
Cardinals D holds 49ers to field goal
The 49ers settled for a field goal for a second time after the Arizona Cardinals defense made a stand. The 49ers had first-and-goal from the Arizona 8. Eventually, that was fourth-and-goal from the 2. Jake Moody kicked the field goal. The drive looked promising for San Francisco with 68 yards gained on 11 plays.
Chad Ryland FG ties game
Trey McBride couldn't hold onto a pass into the end zone and the Cardinals settled for a field goal. Still, the 30-yard kick by Chad Ryland tied the game at 10. Ryland was elevated from the practice squad with Matt Prater injured. Ryland played for the Patriots in 2023.
Purdy to Kittle TD puts 49ers ahead
Brock Purdy from George Kittle for a 4-yard touchdown pass. It capped a 76-yard drive that took 7:11 off the clock. Purdy is 7-for-12 for 119 yards and a touchdown. He's been sacked once. Brandon Aiyuk has four catches for 91 yards. The touchdown is Kittle's only reception.
San Francisco gets on board with FG
After a 53-yard pass from Brock Purdy to Brandon Aiyuk, it looked like the 49ers would answer Arizona's touchdown with one of their own. That didn't happen. Instead, the Cardinals defense held the 49ers to a 28-yard field goal. After the field goal, Arizona went three-and-out. After a punt by Blake Gillikin, the 49ers began their next possession at their own 24.
Kyler Murray making magic
On the Cardinals first offensive snap, Kyler Murray completed a 22-yard pass to Trey McBride. On the second, Murray called his own name and ran 50 yards for a touchdown. The drive lasted just 47 seconds. The run was the longest of Murray's professional career.
Arizona Cardinals kickoff to 49ers
Chad Ryland kicked off for the Arizona Cardinals with Matt Prater inactive. The kickoff was a touchback. The 49ers started at their own 30 and went three-and-out.
Cardinals going all white
The Arizona Cardinals will be going with an all-white look against the 49ers. for the game.
Cardinals without K Matt Prater
Cardinals kicker Matt Prater is inactive for the team's game against the 49ers on Sunday. Prater, 40, was listed as questionable earlier in the week with a knee injury. Chad Ryland was elevated from the practice squad. Prater is 6-for-6 on field goal attempts this season with a long of 57 yards. He is 10-for-10 on extra points. Ryland played 23 games for the New England Patriots in 2023. He is 16-for-25 in his career on field goals and 25-for-26 on point after attempts.
Cardinals vs 49ers schedule: What time is NFL Week 5 game?
The game is on Sunday, Oct. 6 at 1:05 p.m. MST, 4:05 p.m. ET.
Cardinals vs 49ers venue: Where is NFL Week 5 game?
The game is being played at Levi's Stadium in Santa Clara, Calif., the home of the 49ers.
NFL power rankings Week 5: Where are Cardinals, 49ers now? Cardinals vs 49ers TV: What channel is NFL Week 5 game on?
The game can be seen on FOX.
Cardinals vs 49ers streaming: How do I watch NFL Week 5 game on livestream?
Streaming options for the game include
FUBO , which offers a free trial, and other streaming services that carry FOX Sports.
NFL Week 5 picks, predictions: Who will win statement games this week? Cardinals vs 49ers announcers: Who is calling the NFL Week 5 game?
Kevin Burkhardt (play-by-play) and Tom Brady (analyst) are scheduled to be the announcers for the Cardinals at 49ers Week 5 NFL game.
Cardinals vs 49ers game odds: Who is favored in NFL Week 5?
The 49ers are a 7.5-point favorite over the Cardinals in
NFL Week 5 odds for the game, courtesy of
BetMGM Sportsbook . San Francisco is -375 on the moneyline, while Arizona is +300. The over/under (point total) is set at 49.5 points.